Effects of inhalation anesthesia on renal function after parenteral liver transplantation in children

Effect of desflurane inhalation anesthesia on renal function after parent - child liver transplantation and its mechanism

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100041620

Enrollment

Unknown

Registered

2021-01-01

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia for pediatric liver transplantation

Interventions

Group D:Desflurane inhalation anesthesia

Group P:Propofol intravenous anesthesia

Eligibility

Sex/Gender

All

Age

No minimum to 3 Years

Inclusion criteria

Inclusion criteria: A. Recipient for children with parent liver transplantation from 0 months to 3 years old; B. First operation; C. Children's end-stage liver disease system (PELD)<20; D. No history of immunosuppressive drugs and hormone use within 1 year;

Exclusion criteria

Exclusion criteria: A. Abnormal preoperative renal function; B. Severe cardiopulmonary or endocrine diseases; C. Congenital vascular malformations affect the surgical procedure; D. Different postoperative immunosuppressive regimens; E. No follow-up conditions.

Design outcomes

Primary

Measure	Time frame
serum creatinine;Urea nitrogen;urea;Cystatin C;Beta 2- microglobulin;Urinary microalbumin;NGAL;MMP;	—

Countries

China

Contacts

Public ContactLiu Wei

Children's Hospital of Chongqing Medical University

faithrefresh@126.com+86 15123201847

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026