Resistance training shows better effects and higher adherence than aerobic training in older adults with COPD and sarcopenia: a cluster randomized controlled trial based on the stage of change theory

Study on the effect and mechanism of resistance training in patients with chronic obstructive pulmonary disease

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100041616

Enrollment

Unknown

Registered

2021-01-01

Start date

2021-02-19

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease

Interventions

the resistance training group:elastic band resistance training

the aerobic training group:aerobic training

Eligibility

Sex/Gender

All

Age

60 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Aged 60 years or over; 2. COPD patients with forced expiratory volume for 1 second divided by forced vital capacity (FEV1 /FVC) of < 0.7 after post-bronchodilator spirometry by GOLD; 3. Met the diagnostic criteria for sarcopenia: a total score of SARC-CalF =11.

Exclusion criteria

Exclusion criteria: 1. Communication disorders: dementia, cognitive impairment or symptomatic psychiatric disorders, hearing impairment or vision disability, unable to understand and speak Mandarin; 2. Pulmonary bullae, pneumothorax, cancer, raccompanied by the serious illness of severe hypertension, unstable angina, myocardial infarction, congestive heart failure, stroke, severe hepatic and renal diseases, undiagnosed but with any associated symptoms or signs; 3. Bilateral calf circumference difference > 3cm; 4. Requirement for long-term oxygen therapy (=15h per day); 5. Acute exacerbation of COPD ( increased dyspnea and /or cough and sputum that worsen within the past 2 weeks preceding randomization); 6. Hampered assessment of muscle strength or use any assistive device for ambulation; 7. Engaged in regular exercise (3 times per week, at least 30 minutes per time) within 6 months before the intervention; 8. Participated in any other clinical trial in the 6 months before screening; 9. No signed an informed consent.

Design outcomes

Primary

Measure	Time frame
FEV1/FVC;exercise capacity;dyspnea ;fatigue;post-intervention adherence;	—

Secondary

Measure	Time frame
the frequency of acute exacerbations;quality of life;Muscle strength and function;	—

Countries

China

Contacts

Public ContactWang Kefang

School of Nursing and Rehabilitation, Shandong University

wangkf@sdu.edu.cn+86 136 4531 9630

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026