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Clinical comparison of Dexmedetomidine and Midazolam for sedation under brachial plexus anesthesia during humeral surgery

Clinical comparison of Dexmedetomidine and Midazolam for sedation under brachial plexus anesthesia during humeral surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000041565
Enrollment
Unknown
Registered
2020-12-29
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper limb fractures

Interventions

group DEX:dexmetidine
group MID:midazolam

Sponsors

The Second Affiliated Hospital of Zhejiang Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 and <= 65 years; 2. ASA grade I-II; 3. Body mass index is within the normal range; 4. Preoperative informed consent was signed; 5. Internal humerus fixation was performed at an appropriate time.

Exclusion criteria

Exclusion criteria: 1. Contraindicated evidence of brachial plexus block; 2. Severe nerve injury of the affected upper limb; 3. Long-term use of psychotropic drugs; 4. Severe disorders of the central system; 5. Language barriers do not accord with the researchers; 6. Severe hypotension, bradycardia and cardiovascular disease; 7. Failure of brachial plexus block to change general anesthesia.

Design outcomes

Primary

MeasureTime frame
Ramsay score;

Secondary

MeasureTime frame
Intraoperative vital signs;The incidence of adverse reactions during operation;The time of eye opening after operation;Anesthetic satisfaction survey within 24 hrs after operation;

Countries

China

Contacts

Public ContactYuebing Li

The Second Affiliated Hospital of Zhejiang Chinese Medical University

lyb1853@zcmu.edu.cn+86 15988121853

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026