Postherpetic neuralgia
Conditions
Interventions
Subacute phase of herpesoster neuralgia Experimental group (B1):Pulsed radiofrequency combined with botulinum toxin type A subcutaneous injection
Subacute phase of herpesoster neuralgia Control group (A1):Pulsed radiofrequency combined with lidocaine subcutaneous injection
Postherpetic neuralgia Experimental group (B2):Pulsed radiofrequency combined with botulinum toxin type A subcutaneous injection
Postherpetic neuralgia Control group (A2):Pulsed radiofrequency combined with lidocaine subcutaneous injection
Sponsors
The Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Age
15 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Those with postherpetic neuralgia lasting for more than 1 month or paroxysmal pain for more than 3 months. 2. Any age or gender. 3. those who do not have significant pain relief from medications and nerve blocks and have a VAS score > 5. 4. those who agree to be admitted and have the ability to understand and answer questionnaires. 5. those who do not have serious cardiovascular or other diseases and can tolerate the procedure. 6. No contraindication to radiofrequency treatment.
Exclusion criteria
Exclusion criteria: 1. Allergic to botulinum toxin type A, lidocaine, dexamethasone; 2. Defective language expression, incapable of autonomous behavior; 3. Psychiatric patients, children, pregnant women, critical care patients; 4. Those with abnormal coagulation function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS score;VRS score;QS sleep quality score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to reduce the dose of oral medication;Rate of development of herpes zoster neuralgia into PHN; | — |
Countries
China
Contacts
Public ContactFubo Li
Department of Pain Management, The Affiliated Hospital of Southwest Medical University
Outcome results
None listed