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Application of artificial intelligence diagnosis system for multimodal presurgical epileptogenic zone localization

Application of artificial intelligence diagnosis system for multimodal presurgical epileptogenic zone localization

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000041530
Enrollment
Unknown
Registered
2020-12-27
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Interventions

Gold Standard:We comformed that the location of epileptogenic zone was correct after surgical resection by paitents' 1 year follow-up result of Engel's grade I or II. Positive pathological findings we
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Sponsors

Xuanwu Hospital of Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the diagnostic criteria of drug-resistant epilepsy have surgical indications; 2. The patients who received MRI (flames, VBM), intracranial electrode electroencephalogram (EEG) and pet were consulted in Xuanwu Hospital of Capital Medical University, Beijing Tiantan Hospital of Capital Medical University and epilepsy center of children's Hospital of Capital Institute of Pediatrics.

Exclusion criteria

Exclusion criteria: 1. The patients who did not undergo the resection of the epilepsy area were discussed through the location examination and the epilepsy consultation; 2. The postoperative pathological results were not one of focal cortical dysplasia (FCD), hippocampal sclerosis, tuberous sclerosis and benign tumors; 3. Engle's III-IV subjects were followed up one year after operation; 4. Patients who can't complete 1-year follow-up.

Design outcomes

Primary

MeasureTime frame
Engel surgery outcome classification;localization of epileptogenic zone;Change in Seizure Rate;quality of life in epilepsy;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactGuojun Zhang

Xuanwu Hospital of Capital Medical University

zgj62051@163.com+86 13671233613

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026