Lung protection
Conditions
Interventions
Group B:Protective lung ventilation
Group C:Protective lung ventilation + dexmedetomidine 0.50 ug·kg-1·h-1
Group D:Protective lung ventilation + dexmedetomidine 0.80 ug·kg-1·h-1
Sponsors
Department of Anesthesiology, Shiyan People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the operation indications and anesthesia requirements; 2. All patients signed informed consent; 3. Approved by the ethics committee of the college; 4. Subjects with normal preoperative pulmonary function test results.
Exclusion criteria
Exclusion criteria: 1. Patients with history of mental illness and nervous system diseases; 2. Patients with severe heart, lung, liver and kidney diseases; 3. Patients with thoracic and spinal deformities; 4. Subjects with long-term smoking history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alveolar arterial oxygen partial pressure;Arterial partial pressure of oxygen;Oxygenation index;Respiratory index;Intrapulmonary shunt rate;Peak airway pressure;Mean airway pressure;Nitric oxide;Postoperative complications;Postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactZheng Min
Graduate School of Hubei Medical College
Outcome results
None listed