The effect of ovary drug-free in vivo activation (Df-IVA) on the reproductive endocrine function and IVF outcomes for the patient with diminished ovarian reserve.

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000041495

Enrollment

Unknown

Registered

2020-12-27

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Intervetion Group:Drug-free in vivo activation, Df-IVA

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1.Less than 40 years; 2.AFC < 5; 3.AMH < 1.2 ng/ml; 4.the oocyte retrival number is less than 3 in the previous IVF cycle with standard protocol.

Exclusion criteria

Exclusion criteria: 1.have genetic disease causing DOR; 2.exposed with treatment causing DOR; 3.with B category infectious disease like HIV; 4.with endometriosis disease; 5.with ovary operation history; 6.with pelvic infection history; 7.with immune system diease; 8.can not stand for laparoscopy operation.

Design outcomes

Primary

Measure	Time frame
the oocyte number in next IVF cycle;the AMH level;the number of good quality embryo in next IVF cycle;	—

Secondary

Measure	Time frame
the AFC in next IVF cycle;the outcome in next IVF cycle;FSH;AFC;	—

Countries

China

Contacts

Public ContactErnest Ng

nghye@hku.hk+86 18033050737

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026