Effect of cerebrospinal fluid drainage on spinal cord protection during total arch replacement of Stanford Type A aortic dissection

Protective effect of preventive cerebrospinal fluid drainage on spinal cord during total arch replacement of Stanford Type A aortic dissection

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000041489

Enrollment

Unknown

Registered

2020-12-27

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stanford type A aortic dissection

Interventions

prevention group:Preventive cerebrospinal fluid drainage

Non-prevention group:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: We enrolled patients who were diagnosed as Stanford type A aortic dissection, underwent total arch replacement, and were at high risk of postoperative spinal cord injury. Preoperative imaging examination showed that the area of the false cavity was >50%, the false cavity was near the spinal cord, and the false cavity involved the intercostal artery.

Exclusion criteria

Exclusion criteria: (1) SCI existed before aortic surgery; (2) History of stroke; (3) Postoperative complications of the central nervous system lead to limb movement and sensory disorders; (4) Postoperative limb ischemia leads to limb movement and sensory disturbance; (5) Patients with contraindications for subarachnoid puncture; (6) Refuse to enroll patients.

Design outcomes

Primary

Measure	Time frame
muscle strength test;MBP;Time of CPB;CSFP;postoperative complications;	—

Countries

China

Contacts

Public ContactChanjuan Gong

The First Affiliated Hospital of Nanjing Medical University/Jiangsu Province Hospital

Lucifer_98@126.com+86 15951893101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026