Management of pain in breast surgery
Conditions
Interventions
Control group:Nil
QLB group:Unilateral or bilateral single quadratus lumborum block was performed after anesthesia induction, and the concentration of PCIA was halved
ESPB group:single erector spinae plane block was performed after anesthesia induction, and the concentration of PCIA was halved
Sponsors
Drum Tower Hospital, Medical College of Nanjing University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Willing to participate in the study and sign the informed consent; 2.Female; 3.ASA physical condition I to III; 4.Aged 18-65 years; 5.Breast surgery (Operation time > 2h).
Exclusion criteria
Exclusion criteria: 1.The subjects and their families refused to finish the clinical study; 2.Known allergic to study drug; 3.Chronic opioid use; 4.Epilepsy,mental retardation; 5.Morbid obesity (BMI>40); 6.Serious cardiovascular adverse events during operation; 7.Other postoperative adverse events such as septic shock,acute renal failure,etc.; 8.When the doctors or researchers violated the principle of the clinical design in the process of clinical research,the ethics committee terminated or suspended th clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The consumption of opioid and non-steroidal anti-inflammatory drugs after operation and;Hemodynamic parameters during operation;The first time of dieting;The first time of activity;The first time of exhausting;Postoperative analgesic dosage;Postoperative nausea and vomiting;Adverse events;Days of hospital stay; | — |
Countries
China
Contacts
Public ContactBingbing Li
Drum Tower Hospital, Medical College of Nanjing University
Outcome results
None listed