digestive tract disease
Conditions
Interventions
Esketamine Group A:Esketamine 0mg/kg + propofol
Esketamine Group B:Esketamine 0.25mg/kg + propofol
Esketamine Group C:Esketamine 0.5mg/kg + propofol
Esketamine Group D:Esketamine 1mg/kg + propofol
Sponsors
Shanghai Children's Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Aged 3~12 years; 2) Due to dyspepsia, gastric ulcer, or other diseases (such as varicose veins, ingestion of foreign bodies and corrosive esophagitis, etc.) need to undergo upper gastrointestinal endoscopy; 3) ASA score is I or II.
Exclusion criteria
Exclusion criteria: 1) Patients with contraindications to general anesthesia; 2) Patients who are tolerant or allergic to esketamine hydrochloride or propofol; 3) Children who are prescribed medications before anesthesia; 4) Past coagulation abnormalities and bleeding tendency; 5) Abnormal liver or kidney function or history of liver or kidney disease; 6) The investigator considers it inappropriate to participate; 7) The child or parents refuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reaction when entering the endoscope; | — |
Countries
China
Contacts
Public ContactYang Shen
Shanghai Children's Medical Center
Outcome results
None listed