Dentin Hypersensitivity
Conditions
Interventions
experimental group:dentifrice containing potassium nitrate, strontium chloride and paeonol
control group:dentifrice contained same grinding material as experimental dentifrice but without potassium nitrate,strontium chloride and paeonol
Sponsors
West China Stomatological Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male or female subjects, aged 18-65 years. 2. Subjects who can continue to participate in the study within 8 weeks. 3. Subjects with at least two allergic teeth, including premolars or anterior teeth, with cervical abrasion or gingival recession. 4. Subjects with reaction readings of 10-30g in the probe test (Yeaple probe). 5. The subjects with Schiff cold air sensitivity index of 2 or 3 were examined by air blowing method. 6. There are two teeth that are not adjacent to each other, and the results of the above two examinations meet the requirements. 7. Subjects with good health were not allergic to the toothpaste. 8. Subjects who did not use desensitization toothpaste within 3 months before participating in the study. 9. Subjects willing to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Subjects with oral mucosal lesions, chronic diseases and allergic history to toothpaste components. 2. Subjects with periodontal disease progression or who have received periodontal treatment (including periodontal surgery) in the past year. 3. Subjects with more than I degree tooth mobility. 4. Subjects with extensive restoration, suspected pulpitis, caries, cracked enamel and removable partial denture. 5. Subjects taking anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory agents and daily analgesics. 6. Subjects who participated in the study of desensitization toothpaste or daily use of desensitization toothpaste in the past 3 months. 7. Subjects who are participating in other clinical studies. 8. Female pregnancy or lactation. 9. Subjects with a history of allergy to personal health care products or their ingredients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tactile test;Airblast test; | — |
Countries
China
Contacts
Public ContactYisi Zhong
West China Stomatological Hospital of Sichuan University
Outcome results
None listed