psoriasis
Conditions
Interventions
singel arm:Guselkumab
Sponsors
Dermatology Hosipital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Aged >= 18 years; 2) Patients with Psoriasis Area Severity Index score (PASI) >= 10; 3) Patients with PASI < 10, who presented with involovement of sensitive areas such as the face, scalp, genital areas or nails. 4) Wash-out period of at least 4 weeks from systemic or UV treatment. 5) Patients were treated with standard dose of guselkumab (100 mg administered by subcutaneous injection at Week 0 and Week 4, followed by a maintenance dose every 8 weeks).
Exclusion criteria
Exclusion criteria: 1) Patients suffer with active infectious diseases, such as active tuberculosis, etc. 2) Patients suffer serious chronic systemic diseases. 3) Women who are pregnant or breastfeeding. 4) Inoculated live virus or live bacteria vaccine within 2 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Psoriasis Area Severity Index;Nail Psoriasis Severity Index;Physician's Global Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatology Life Quality Index;Skindex-16;Frequency of related immune cells;Related immunocytokine; | — |
Countries
China
Contacts
Public ContactYongfeng Chen
Dermatology Hosipital of Southern Medical University
Outcome results
None listed