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Efficacy and safety of porcine collagen combined botulinum toxin for the facial rejuvenation: a prospective self-control study

Efficacy and safety of porcine collagen combined botulinum toxin for the facial rejuvenation: a prospective self-control study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000041367
Enrollment
Unknown
Registered
2020-12-24
Start date
2021-02-20
Completion date
Unknown
Last updated
2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin aging

Interventions

single arm:mesotherapy

Sponsors

The Sixth People's Hospital Affiliated to Shanghai Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Healthy women aged 30 to 50 years. 2. Subjects with dry, loose, dark, fine lines, coarse pores and other aging symptoms. 3. Subjects who have informed consent to the project, and sign the informed consent form of the project, and are willing to comply with the test requirements, and can complete the follow-up according to the requirements. 4. During the study period, we can strictly prevent the sun, do not inject any products other than this study, do not do medical and aesthetic projects such as laser, hot Maggie, ultrasonic scalpel, and avoid strenuous exercise to reduce sweating as much as possible.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating subjects. 2. Subjects sensitive to medical procedures such as botulinum toxin and collagen injection. 3. Subjects with a history of laser, intermediate therapy, chemical peeling or plastic surgery in the last three months. 4. Subjects who have experienced autoimmune diseases, connective tissue diseases, any systemic organic diseases, such as heart and kidney diseases, and who are currently suffering from skin diseases or inflammation.

Design outcomes

Primary

MeasureTime frame
Feature counts measured by VISIA;skin hydration;

Countries

China

Contacts

Public ContactHaiyan Jiang

The Sixth People's Hospital Affiliated to Shanghai Jiaotong University

80140384@qq.com+86 13371819109

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026