postoperative pain after craniotomy
Conditions
Interventions
Group R:0.25% ropivacaine 30ml
Group RM: Dexmedetomidine 1 ug / kg + 0.25% ropivacaine, 30ml in total
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with preoperative intracranial space occupying or intracranial vascular diseases should be selected for craniotomy; 2. Patients with ASA grade I-III had no severe cardiopulmonary and other systemic and mental diseases; 3. The subjects had informed consent to the study, and the degree of cooperation was good.
Exclusion criteria
Exclusion criteria: 1. Patients whose incision is beyond the block area; 2. Patients with operation time more than 6 hours; 3. Patients with obvious abnormal heart, liver and kidney function, severe electrolyte disorder and obvious organic diseases before operation; 4. Patients with bradycardia and heart block; 5. Patients with allergic history of any research drug or anesthetic, history of chronic pain, long-term use of opioids or benzodiazepines; 6. Patients with preoperative disturbance of consciousness and abnormal communication have postoperative cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale/Score (VAS);blood pressure;heart rate;Ramsay score; | — |
Countries
China
Contacts
Public ContactChen Chen
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed