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Withdraw Application of opioid-sparing multimodal anesthesia based on ultrasound-guided scalp nerve block in craniotomy

Withdraw Application of opioid-sparing multimodal anesthesia based on ultrasound-guided scalp nerve block in craniotomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000041361
Enrollment
Unknown
Registered
2020-12-24
Start date
2020-12-24
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial Lesions

Interventions

Group B:ropivacaine scalp block combined general anesthesia

Sponsors

Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The subjects with clear diagnosis of intracranial space occupying or intracranial vascular diseases before operation were selected for craniotomy; 2. ASA I-III subjects had no severe cardiopulmonary and other systemic and mental diseases; 3. The subjects had informed consent to the study, and the degree of cooperation was good.

Exclusion criteria

Exclusion criteria: 1. Patients whose incision is beyond the block area; 2. Patients with operation time more than 6 hours; 3. Patients with obvious abnormal heart, liver and kidney function, severe electrolyte disorder and obvious organic diseases before operation; 4. Patients with bradycardia and heart block; 5. Patients with allergic history of any research drug or anesthetic, history of chronic pain, long-term use of opioids or benzodiazepines; 6. Patients with preoperative disturbance of consciousness and abnormal communication have postoperative cognitive dysfunction.

Design outcomes

Primary

MeasureTime frame
dosage of opioids during surgery;dosage of general anesthetics during surgery;extubation time;awake time;heart rate;blood pressure;postoperative VAS score;dosage of analgesics postoperative;

Secondary

MeasureTime frame
Postoperative adverse reactions;

Countries

China

Contacts

Public ContactChen Chen

The First Affiliated Hospital of Anhui Medical University

cc3014@126.com+86 15922410728

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026