Intracranial Lesions
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The subjects with clear diagnosis of intracranial space occupying or intracranial vascular diseases before operation were selected for craniotomy; 2. ASA I-III subjects had no severe cardiopulmonary and other systemic and mental diseases; 3. The subjects had informed consent to the study, and the degree of cooperation was good.
Exclusion criteria
Exclusion criteria: 1. Patients whose incision is beyond the block area; 2. Patients with operation time more than 6 hours; 3. Patients with obvious abnormal heart, liver and kidney function, severe electrolyte disorder and obvious organic diseases before operation; 4. Patients with bradycardia and heart block; 5. Patients with allergic history of any research drug or anesthetic, history of chronic pain, long-term use of opioids or benzodiazepines; 6. Patients with preoperative disturbance of consciousness and abnormal communication have postoperative cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| dosage of opioids during surgery;dosage of general anesthetics during surgery;extubation time;awake time;heart rate;blood pressure;postoperative VAS score;dosage of analgesics postoperative; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative adverse reactions; | — |
Countries
China
Contacts
The First Affiliated Hospital of Anhui Medical University