Hypotension in cesarean section
Conditions
Interventions
Group 1:metaraminol 0.75 ug·kg-1·min-1
Group 2:metaraminol 1.5ug·kg-1·min-1
Group 3:metaraminol 2.25ug·kg-1·min-1
Group 4:metaraminol 3ug·kg-1·min-1
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Full-term women aged 18-35 yr with singleton pregnancyscheduled for elective Caesarean delivery.
Exclusion criteria
Exclusion criteria: ASA physical status >= 3, obesity (BMI > 30kg·m-2), height < 150cm , early or active labour, pre-existing or pregnancy-induced hypertension, diabetes mellitus, significant cardiovascular or cerebrovascular disease, known fetal abnormality, intrauterine growth restriction, obstetric complication (ruptured membranes, placenta praevia, placental abruption), and any contraindication tospinal or epidural anaesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Umbilical artery blood pH;umbilical vein blood PH;umbilical artery blood partial pressure of oxygen;umbilical vein blood partial pressure of oxygen;umbilical artery blood BE;umbilical vein blood BE;umbilical artery blood HCO3-;umbilical vein blood HCO3-;fetal Apgar score (1 minute and 5 minutes after birth);The incidence of nausea in pregnant women;The incidence of vomiting in pregnant women; | — |
Countries
China
Contacts
Public ContactDunyi Qi
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed