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Observation of vascular changes in ocular fundus of hypertension by OCTA based on deep learning

Observation of vascular changes in ocular fundus of hypertension by OCTA based on deep learning

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000041330
Enrollment
Unknown
Registered
2020-12-23
Start date
2021-01-11
Completion date
Unknown
Last updated
2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensive retinopathy

Interventions

hypertension group and healthy control group:nil

Sponsors

Department of Ophthalmology, the First Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged >= 16 years and <= 80 years with essential hypertension diagnosed in our department. 2. The subjects in the hypertension group and the healthy control group had no history of other systemic diseases or other intraocular diseases (including diabetic retinopathy, macular edema, macular hole, epimacular membrane, age-related macular degeneration, retinal detachment, retinal vascular occlusion, central serous chorioretinopathy, uveitis, optic neuropathy, etc.). 3. There was no history of intraocular surgery, intraocular injection, fundus laser, ocular trauma, glaucoma and suspected glaucoma (large cup-disc ratio, asymmetric cup-disc ratio, defect or narrow rim, optic disc hemorrhage or suspected changes of nerve fiber layer). 4. First-degree family members of non-glaucoma patients.

Exclusion criteria

Exclusion criteria: Do comprehensive physical examination and eye examination for patients, including systemic examination, best corrected visual acuity, intraocular pressure, eye axis measurement, computer optometry, slit lamp examination, fundus photography, OCTA. The exclusion criteria included: 1. Primary or other secondary retinal diseases; 2. inability to complete OCTA examination; 3. severe corneal leukoplakia, cataract, strabismus, nystagmus, etc.; 4. severe ametropia (> + 300 / <-600); 5. IOP was not in the range of 10-21mmHg; 6. OCTA scan quality < 7.

Design outcomes

Primary

MeasureTime frame
OCTA;

Secondary

MeasureTime frame
Blood pressure;

Countries

China

Contacts

Public ContactZhang Hong

Department of Ophthalmology, the First Affiliated Hospital of Harbin Medical University

eason_ting@126.com18103637370

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026