Cervical cancer
Conditions
Interventions
1:Radical hysterectomy
2:Concurrent chemotherapy and radiotherapy
Sponsors
Obstetrics and Gynecology Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients clinically diagnosed with locally advanced cervical cancer: IB3, iia2, iiicr (only suspected lymph node positive by imaging); 2. Patients with preoperative pathological diagnosis of cervical squamous cell carcinoma, cervical adenosquamous cell carcinoma or cervical adenocarcinoma; 3. Patients whose age is less than or equal to 70 years old; 4. Physical strength grade: Karnofsky score >= 60; 5. The patients who were treated for the first time; 6. The patients who volunteered to join the study signed informed consent, good compliance, and cooperated with follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients who can't accept surgery because of various surgical contraindications; 2. Patients who received pelvic / abdominal radiotherapy or chemotherapy in the past; 3. Patients with distant metastasis indicated by CT, MRI or pet; 4. Preoperative imaging and physical examination showed that there was no parametrial involvement, no extension to the pelvic wall, and no involvement in the lower third of vagina.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence-free survival;Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications;Quality of life; | — |
Countries
China
Contacts
Public ContactKeqin Hua
Obstetrics and Gynecology Hospital Affiliated to Fudan University
Outcome results
None listed