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Study on using proteomics and metabolomics for screening biomarkers of polycystic ovary syndrome

Study on using proteomics and metabolomics for screening biomarkers of polycystic ovary syndrome

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000041273
Enrollment
Unknown
Registered
2020-12-23
Start date
2018-12-01
Completion date
Unknown
Last updated
2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovary syndrome

Interventions

healthy control group:None

Sponsors

Zhejiang Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 37 Years

Inclusion criteria

Inclusion criteria: The diagnostic criteria were based on the Chinese Guidelines for the Treatment of Polycystic Ovarian Syndrome (PCOS) formulated by the Endocrinology Group of the Chinese Society of Obstetrics and Gynecology and the Guidelines Expert Group in 2018: scanty menstruation or amenorrhea or irregular uterine bleeding were required for the diagnosis. In addition, one of the following two criteria must be met: (1) Clinical manifestation of hyperandrogenism or hyperandrogenemia; (2) Ultrasound manifestation of polycystic ovarian changes PCOM: ultrasound indicates >= 12 follicles of 2-9 mm in diameter and/or ovarian volume >= 10 ml in one or both ovaries. The healthy control group was obtained from the health checkup center of the Zhejiang Provincial Hospital of Chinese Medicine. All healthy control enrollees were required to have a normal menstrual cycle (25-35 days) without clinical and/or biochemical hyperandrogenic manifestations.

Exclusion criteria

Exclusion criteria: Exclude people taking hormonal drugs in the last 3 months or using drugs that affect insulin sensitivity (such as metformin, etc.), people with severe liver, kidney, lung, hematopoietic insufficiency and heart diseases, autoimmune diseases, etc.

Design outcomes

Primary

MeasureTime frame
Biomarker;

Countries

China

Contacts

Public ContactYu Ying

Zhejiang Provincial Hospital of Chinese Medicine

yuying721030@163.com+86 15967182453

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026