acute pancreatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Informed consent form obtained from the patient or next of kin; 2. Aged between 18 to 70 years; 3. Symptoms and signs of acute pancreatitis based on abdominal pain suggestive of AP, serum amylase at least three times the upper limit of normal, and/or characteristic findings of AP on computed tomography or less commonly magnetic resonance imaging (MRI) or transabdominal ultrasonography according to the Revised Atlanta Criteria; 4. Infected necrosis is diagnosed by gas in the necrotic collection on imaging, positive culture of a fine-needle aspiration (FNA), or unequivocal clinical signs of infection.
Exclusion criteria
Exclusion criteria: 1. Pregnant pancreatitis; 2. Receiving intervention or early surgery due to abdominal compartment syndrome or other reasons before admission ; 3. Patients with a known history of severe cardiovascular, respiratory, renal, hepatic, hematologic, or immunologic disease defined as (1) greater than New York Heart Association class III heart failure, (2) active myocardial ischemia or (3) cardiovascular intervention within previous 60 days, (4) history of cirrhosis or (5) chronic kidney disease with creatinine clearance< 40 mL/min, or (6) chronic obstructive pulmonary disease with requirement for home oxygen. 4. Patients with preexisting immune disorders such as AIDS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of in-hospital death and major complications; | — |
Countries
China
Contacts
General Hospital of the PLA Eastern Theater Command