Postoperative sleep disorders
Conditions
Interventions
Propofol group:Anesthesia maintenance: Propofol TCI: 3-4ug / ml Sufentanil 0.3-0.5 µg / (kg·h) Cisatracurium 1-3 µg / (kg·min)
Desflurane group:Anesthesia maintenance: Desflurane inhalation (MAC 1.0-1.2) Sufentanil 0.3-0.5 µg / (kg·h) Cisatracurium 1-3 µg / (kg·min)
Sponsors
Zhongnan Hospital of Wuhan University
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Undergoing elective breast surgery 2. Age 18-75 years old 3. ASA-PS grade I or II 4. Those who voluntarily participate in the research and sign the informed consent
Exclusion criteria
Exclusion criteria: 1. Cognitive impairment (MMSE <27) before the operation 2. The patients received adjuvant chemotherapy before the operation 3. At present, they are taking psychoactive, opioid, anti-anxiety, or hypnotic drugs 4. Known or treated patients with obstructive sleep apnea 5. Patients with other cancers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index scores;Total sleep time (TST), Rapid eye movement time (REM), Wakefulness after sleep onset (WASO);Self-Rating Anxiety Scale Scores;Self-Rating Depression Scale Scores;Visual analogue scale scores;Flurbiprofen dose; | — |
Countries
China
Contacts
Public ContactPeng Mian
Zhongnan Hospital of Wuhan University
Outcome results
None listed