Pediatric obstructive sleep apnea hypopnea syndrome and saliva microbiome

Saliva microbiome of pediatric obstructive sleep apnea hypopnea syndrome

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000041263

Enrollment

Unknown

Registered

2020-12-23

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric obstructive sleep apnea hypopnea syndrome

Interventions

Pediatric obstructive sleep apnea hypopnea syndrome group:Nil

healthy control group:Nil

Eligibility

Sex/Gender

All

Age

3 Years to 14 Years

Inclusion criteria

Inclusion criteria: Children aged 3~14 years with obstructive sleep apnea hypopnea syndrome diagnosed by polysomnography.

Exclusion criteria

Exclusion criteria: 1. Oral diseases: DFMT >= 4 or bleeding index BI >= 3 or average periodontal pocket depth PD >= 3mm or other oral diseases (oral mucous membrane disease, oral tumor/oral cancer); 2. Any active infection (i.e., bacterial, fungal or viral) and systemic disease (lung, liver, kidney, cardiovascular, gastrointestinal, neurological, endocrine, immune, etc.) that may affect oral flora; 3. Congenital malformations or genetic syndromes (such as cleft lip and palate, Downs syndrome, Crozon syndrome, etc.); 4. Central or mixed sleep apnea.

Design outcomes

Primary

Measure	Time frame
oral microbiota;	—

Countries

China

Contacts

Public ContactGao Xuemei

Peking University School and Hospital of Stomatology

xmgao@263.net+86 10-82195739

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026