The effects of norepinephrine and phenylephrine on cerebral oxygenation in treating intraoperative hypotension in STA-MCA bypass surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000041260

Enrollment

Unknown

Registered

2020-12-23

Start date

2021-01-01

Completion date

Unknown

Last updated

2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moyamoya disease

Interventions

Group 1:iv norepinephrine

Group 2:iv phenylephrine

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA 2-3, age 18-65 years, sinus rhythm, Hb>10g/dl, plan to have STA-MCA bypass surgery.

Exclusion criteria

Exclusion criteria: Sinus bradycardia, uncontrolled hyperblood pressure, ie SBP > 160mmHg, coronary artery disease, heart valve disease, hepatic or renal disfunction.

Design outcomes

Primary

Measure	Time frame
cerebral oxygennation;	—

Secondary

Measure	Time frame
musle oxygenation;urine output;Lactate;tissue oxygen extraction;hepatic function;renal function;neurological complication;length of hospital stay;motality in 90days;MMSE score;QoR 15 score;S100B;oxygen extraction rate;	—

Countries

China

Contacts

Public ContactSheng Wang

The South District of Anhui Provincial Hospital

18935701573@163.com+86 18935701573

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026