pulmonary hypertension
Conditions
Interventions
Gold Standard:1. Diagnostic criteria for pulmonary hypertension: At rest, right heart catheter detected mPAP >= 25mmHg.
2. Diagnostic criteria for right cardiac insufficiency: cardiac MRI measurement,
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Sponsors
The Second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Pulmonary hypertension diagnosis and grading criteria: At rest, right heart catheter detected mPAP >= 25mmHg.According to the degree of PASP elevation, the patients were further divided into: mild pulmonary hypertension: 30mmHg = 70mmHg. (2) The following types of pulmonary hypertension patients were enrolled: Idiopathic pulmonary hypertension. Connective tissue disease correlation between pulmonary hypertension; Left to right shunt congenital heart disease, surgical/interventional postoperative pulmonary hypertension; Chronic thromboembolic pulmonary hypertension; Blood system diseases related to pulmonary hypertension. (3) Sinus rhythm; (4) Aged 18 years; (5) Good compliance, agree to participate in this study, and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with other types of pulmonary hypertension (e.g., left heart disease-associated pulmonary hypertension); (2) Right bundle branch block; (3) Patients with a history of mental illness, drug addiction or other diseases cannot sign informed consent or cooperate with the study; (4) The presence of an acute/chronic organic disease (except dyspnea) prevents the patient from completing the required items in the study; (5) Those whose condition is unstable; (6) Pregnant and breast-feeding patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mPAP;PAWP;RVEF;Right atrium left and right diameter(RAD 1);Right atrium length diameter (RAD 2);Right atrium area;Inner diameter of the right ventricular outflow tract;Right ventricluar left and right diameter;Right ventricular length diameter;Right ventricular wall thickness;Right ventricular area;TAPSE;S';FAC;E/A;E/e';Internal diameter of inferior vena cava;Inferior vena cava collapse rate;TR;RVGLS;PASP;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactBu Rui
The Second Affiliated Hospital of Kunming Medical University
Outcome results
None listed