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Effect of esketamine in anesthesia of vocal cord polypectomy under suspension laryngoscope. A randomized controlled study

Effect of esketamine in anesthesia of vocal cord polypectomy under suspension laryngoscope. A randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000041187
Enrollment
Unknown
Registered
2020-12-21
Start date
2020-12-23
Completion date
Unknown
Last updated
2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vocal cord polyp

Interventions

Experimental group:Intravenous ketamine (0.5 mg/kg) before surgery
Control group:Intravenous sufentanil (0.125µg/kg) before surgery

Sponsors

Xiangya Hospital Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20-70 years; 2. ASA grades I to III; 3. Patients who received supportive laryngoscope operation for vocal cord polyp for the first time.

Exclusion criteria

Exclusion criteria: 1. Patients who are allergic to the active ingredient or all excipients of estelline ketamine; 2. Patients with a serious risk of increased blood pressure or intracranial pressure; 3. Patients with poorly controlled or untreated hypertension; 4. Untreated or undertreated hyperthyroidism (hyperthyroidism); 5. Patients with ischemic heart disease or arrhythmia; 6. Patients with or with a history of mental disorders; 7. Patients with glaucoma or other diseases that cannot withstand increased intraocular pressure; 8. Patients with severe liver and renal insufficiency; 9. Pregnant and lactating patients.

Design outcomes

Primary

MeasureTime frame
Heart rate;non-invasive blood pressure;

Countries

China

Contacts

Public ContactChangsheng Huang

Xiangya Hospital Central South University

changsheng.huang@csu.edu.cn+86 731-84327413

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026