Atrial fibrillation
Conditions
Interventions
Observation group:30 minutes after the first PVI, the operation was finished when the electrical conduction of PV-LA was not recovered, and the electrical conduction of PV-LA was ablated again until t
Adenosine triphosphate group:30 minutes after the first PVI, adenosine triphosphate (ATP) (30mg / 40mg) was injected intravenously to end the operation without recovery of PV-LA conduction, and the PV
Adenosine triphosphate + electrical stimulation group:30 minutes after the first PVI, pacing on the ablation line (voltage 5V, pulse width 2ms) could not capture the end of the operation of the atrium
Sponsors
Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 85 years; (2) diagnosis of paroxysmal atrial fibrillation or persistent atrial fibrillation (duration of atrial fibrillation <=12 months), failed by at least one antiarrhythmic drug treatment, proposed transcatheter radiofrequency ablation; (3) New York Heart Association (NYHA) class I or II cardiac function before operation.
Exclusion criteria
Exclusion criteria: 1. Complicated with valvular heart disease, hypertrophic cardiomyopathy, primary dilated cardiomyopathy, mitral and / or aortic valve biological or mechanical valve replacement; 2. radiofrequency ablation without radiofrequency ablation due to surgical contraindications; 3. if there are operative complications during the operation and fail to achieve the scheduled operation target; 4. the atrial fibrillation can not be terminated after reaching the scheduled operation target; 5. the follow-up can not be carried out at the prescribed time after operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of postoperative atrial fibrillation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac Function; | — |
Countries
China
Contacts
Public ContactJianhua Chen
Fujian Medical University
Outcome results
None listed