Colorectal surgery
Conditions
Interventions
1:Parecoxib
2:Normal saline
Sponsors
The First Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Colorectal surgery including radical resection of colorectal cancer, subtotal colectomy for chronic constipation and other laparoscopic and conventional open surgery is required after the diagnosis is clear. (2) The age is between 18 and 80 years old. (3) Ability to communicate in normal language (4) No movement disorder and no mood or mental cognitive impairment determined by psychological evaluation (5) Patients or family members, able to understand the research plan and willing to participate in this research, and provide written informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with history of allergy to the active ingredient of parecoxib sodium for injection or any ingredient in excipients, patients with liver and kidney dysfunction, and patients with cardiopulmonary insufficiency. (2) After starting the treatment, after careful distinction, for cases that do not meet the requirements of the design plan or may affect the test results. (3) Cases with poor compliance with the test. (4) People who are dependent on painkillers. (5) The patient has serious adverse reactions or cannot tolerate adverse reactions. (6) Those who withdraw from the experiment before the treatment is over, such as death, automatic discharge, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery of bowel function; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Countries
China
Contacts
Public ContactAn-Long Zhu
The First Affiliated Hospital of Harbin Medical University
Outcome results
None listed