CLINICAL EFFECTS OF METHYLTHIONINE CHLORIDE CONTINUOUS THORACIC PARAVERTEBRAL BLOCK IN POSTHERPETIC NEURALGIA

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000041155

Enrollment

Unknown

Registered

2020-12-19

Start date

2020-12-22

Completion date

Unknown

Last updated

2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

POSTHERPETIC NEURALGIA

Interventions

MB group:continuous thoracic paravertebral block with methylene blue

NTP:continuous thoracic paravertebral block with NTP

Combination group:continuous thoracic paravertebral block with methylene blue and NTP

control group:continuous thoracic paravertebral block with local anesthetic

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged >= 18 years; 2. Patients were clearly diagnosed with PHN before 1-12 months, and the involved segment is T1~T12; 3. Patients present with skin neuropathic pain currently, and the pain number score NRS(numerical rating scale)> 6 points;

Exclusion criteria

Exclusion criteria: 1. Patients have severe dysfunction of heartlungliverkidneyand the blood system; 2. Patient have acute general infection; 3. Patients have skin damage or local infection at the puncture site; 4. Patients with hemostatic disturbances; 5. Patients are allergic to drugs used in this study or are not suitable for nerve blockade; 6. Intravenous or oral NTP and methylene blue had been used to patients after the onset of herpes zoster;

Design outcomes

Primary

Measure	Time frame
NRS;	—

Secondary

Measure	Time frame
The Patient Health Questionnaire-9;Insomnia Severity Index;score;	—

Countries

China

Contacts

Public ContactWang Mingxia

Shanghai East Hospital

amymingxia@163.com+86 18835173975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026