Carbapenem-resistant Organism pulmonary infection
Conditions
Interventions
grouped according to different administration methods:NIl
Sponsors
The Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients over 18 years old; 2. Patients who used polymyxin B in the treatment of cro pulmonary infection, and the treatment time of polymyxin B was more than 72 hours; 3. For patients who use polymyxin B repeatedly, the treatment period with the first polymyxin B treatment time >= 72 hours shall prevail; 4. Patients with definite pathogen results and drug sensitivity results indicating resistance to carbapenems; 5. Patients who volunteered to join the study signed informed consent, allowing researchers to use clinical data for research analysts.
Exclusion criteria
Exclusion criteria: 1. Pregnant, planned or lactating women; 2. Patients undergoing cardiopulmonary resuscitation in ICU; 3. Patients with advanced malignant tumor and HIV infection; 4. Patients allergic to polymyxin B; 5. Patients with history of asthma; 6. Subjects who are participating in other clinical studies within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mortality;clinical cure;bacterial clearance time;Length of ICU stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Noninvasive/invasive mechanical ventilation time;Oxygenation index;Change of infection index;Body temperature changes; | — |
Countries
China
Contacts
Public ContactWang Gang
The Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed