Renal damage in elderly patients with hypertension
Conditions
Interventions
normal baPWV group and abnormal baPWV group:Nil
Sponsors
Tianjin First Central Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Patients over 60 years old; 2. Patients diagnosed with essential hypertension according to the European hypertension management guidelines 2018; 3. Patients who signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with primary renal damage (short course of hypertension; simple renal hematuria or proteinuria with hematuria; rapid deterioration of renal function in a short time; sudden edema and large amount of proteinuria with normal renal function; combined with obvious abnormal tube type); 2. Patients with immune system diseases and thyroid dysfunction; 3. Patients with secondary hypertension, malignant hypertension and hypertension emergency; 4. Patients with diabetes, coronary heart disease, peripheral vascular disease, rheumatic heart disease, congenital heart disease, etc; 5. Patients with severe cardiac insufficiency, severe liver and kidney insufficiency; 6. Patients taking nephrotoxic drugs for a long time; 7. Patients with recent cerebral hemorrhage, urinary system diseases, severe infection, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pulse wave velocity;creatinine;urine microalbumin;Glomerular filtration rate;Urinary microalbumin / creatinine ratio;Urea nitrogen;Serum cystatin C; | — |
Secondary
| Measure | Time frame |
|---|---|
| Homocysteine; | — |
Countries
China
Contacts
Public ContactWang Xuena
Tianjin First Central Hospital
Outcome results
None listed