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Multi-center, randomized, controlled, non-inferiority clinical trial of early enteral nutrition after endoscopic resection of colorectal polyps

Multi-center, randomized, controlled, non-inferiority clinical trial of early enteral nutrition after endoscopic resection of colorectal polyps

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000041116
Enrollment
Unknown
Registered
2020-12-18
Start date
2021-02-07
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonic polyps

Interventions

Group A:Early enteral nutrition
Group B:Parenteral nutrition

Sponsors

Sun Yat-Sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged from 18 to 75, regardless of gender; 2. Patients with good cardiopulmonary function, normal blood routine and bleeding and clotting time, and can tolerate anesthesia and surgical treatment; 3. Patients with intestinal polyps found by colonoscopy; 4. Patients after endoscopic polypectomy (EMR, ESD); 5. The subjects who can understand the purpose of the experiment voluntarily participate and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with special types of polyps, such as familial polyposis, etc.; 2. Patients with liver and kidney insufficiency, metabolic acidosis, plasma TG > 200mg / dl, TB > 10mg / dl are not suitable for intravenous nutrition; patients with special nutritional needs (diabetic patients, etc.); 3. Patients with enteral nutrition contraindications, active gastrointestinal bleeding, severe esophageal and gastric varices, intestinal obstruction, abdominal compartment syndrome, acute episode of inflammatory bowel disease, etc.; 4. Subjects with lactose intolerance, milk or soybean allergy; 5. Patients with recent active hemorrhoids bleeding; 6. Patients with poor constitution or other serious diseases, such as myocardial infarction, unstable angina pectoris, stroke or transient ischemic attack (TIA), malignant arrhythmia, heart failure, liver and kidney failure, etc.; 7. Patients who have recently undergone digestive tract surgery such as esophagus, stomach and colorectal surgery; 8. Subjects who were pregnant or planned to be pregnant in the near future; 9. The researchers judged that the subjects with poor compliance did not follow the doctor's advice; 10. Patients who participated in other clinical studies in recent 3 months; 11. Patients with present malignant tumor; 12. Patients taking hormone, immunosuppressant and anticoagulant / antiplatelet drugs within 2 weeks; 13. Patients in other situations considered unsuitable by the researchers.

Design outcomes

Primary

MeasureTime frame
Complication rate;

Secondary

MeasureTime frame
Postoperative comfort score;Hospital stay;Hospital costs;

Countries

China

Contacts

Public ContactGuoliang Xu

Sun Yat-Sen University Cancer Center

xugl@sysucc.org.cn+86 189 0305 3630

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026