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Biomechanically based study of cardiovascular risk in patients with knee osteoarthritis

Biomechanically based study of cardiovascular risk in patients with knee osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000041115
Enrollment
Unknown
Registered
2020-12-18
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Knee osteoarthritis with a moderate to high risk of cardiovascular disease:Nil
Knee osteoarthritis with no or low risk of cardiovascular disease:Nil
No KOA symptoms group:Nil

Sponsors

The Third People's Hospital affiliated to Fujian University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with KOA: (1) According to the diagnostic criteria of knee osteoarthritis. (2) Imaging diagnosis of osteophyte formation of knee joint. (3) The imaging diagnosis of medial compartment osteophyte of knee joint was made in 38-80 years old. (4) Kellgren / Lawrence (K / L) test confirmed that the joint space was narrow, sclerotic and possibly deformed. (5) Patients who volunteered and signed informed consent. 2. Subjects without koa symptoms: (1) According to the diagnosis of clinicians, there was no knee osteoarthritis symptoms and diagnosis. (2) They were 50-80 years old. (3) Volunteers who signed informed consent. Those meeting the above criteria could be included in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with various acute, infectious and infectious diseases and visceral dysfunction. 2. Patients suffering from other diseases of nervous system or musculoskeletal system that affect gait, such as stroke and other neurogenic joint diseases, fractures, rheumatoid arthritis, etc. 3. Kellgren / Lawrence (K/L) grade 0: normal; grade 1: suspected joint space stenosis and possible labial hyperplasia; or grade 4: large osteophyte, obvious joint space stenosis, severe sclerosis and definite bone end deformation.

Design outcomes

Primary

MeasureTime frame
WOMAC;3D motion analysis;Cardiopulmonary Exercise Test;surface electromyagram;

Countries

China

Contacts

Public ContactXuerong Xie

The Third People's Hospital affiliated to Fujian University of Traditional Chinese Medicine

715685384@qq.com+86 13305916706

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026