The clinical effect of xenogeneic collagen matrix and free gingival graft in jaws reconstructed with fibula or iliac bone flaps

Keratinized mucosa augmentation around implants in jaws reconstructed with fibula or iliac bone flaps

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000041104

Enrollment

Unknown

Registered

2020-12-17

Start date

2020-12-17

Completion date

Unknown

Last updated

2022-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal diseases

Interventions

1:Free gingival graft plus collagen sponge

2:Free gingival graft plus xenogeneic collagen matrix

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: After 3-6 months of implant placement, the patients after jaw reconstruction need to be treated with keratinized mucosa augmentation before implant repair.

Exclusion criteria

Exclusion criteria: 1. Patients who refused to participate in this study; 2. Patients who cannot complete follow-up treatment due to disease recurrence; 3. Pregnant or lactating subjects; 4. Patients with uncontrolled systemic diseases; 5. Heavy smoker of more than 10 cigarettes per day.

Design outcomes

Primary

Measure	Time frame
Keratinized mucosa width;Soft tissue thickness;	—

Secondary

Measure	Time frame
The depth of vestibular groove;Shrinkage of keratinized tissue shrinkage;Histopathological analysis of the augmented keratinized tissue;Patient-centered evaluation;Peri-implant pocket depth;	—

Countries

China

Contacts

Public ContactLu Ruifang

Peking University School and Hospital of Stomatology

kqrflu@bjmu.edu.cn+86 10 82195368

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 17, 2026