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Clinical outcomes of CCTA combined with ct-mpi and CCTA combined with ct-ffr in guiding treatment strategies for patients with stable chest pain

Clinical outcomes of CCTA combined with ct-mpi and CCTA combined with ct-ffr in guiding treatment strategies for patients with stable chest pain

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000041102
Enrollment
Unknown
Registered
2020-12-17
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

Group 1:CCTA+CT-MPI
Group 2:CCTA+CT-FFR

Sponsors

The Sixth People's Hospital Affiliated to Shanghai Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with stable angina pectoris or atypical chest pain; 2. According to the updated diamond Forrester score, the patients with high and medium probabilities (= 15%) of CAD were evaluated; 3. Patients over 18 years old.

Exclusion criteria

Exclusion criteria: 1. Patients with previous history of myocardial infarction or revascularization therapy; 2. Patients with severe arrhythmia; 3. Patients suspected of cardiomyopathy and other diseases affecting myocardial blood flow; 4. Patients with renal insufficiency; 5. Patients allergic to iodine contrast agent; 6. Patients with contraindications of ct-mpi examination (bronchial asthma, hypotension, degree III atrioventricular block).

Design outcomes

Primary

MeasureTime frame
unnecessary ICA within 90 days;

Secondary

MeasureTime frame
A composite of major adverse cardiac events at 1 year;symptom change at 1 year;the rate of late revascularization after CT examination;overall radiation dose;overall contrast media usage;overall medical cost;

Countries

China

Contacts

Public ContactJiayin Zhang

The Sixth People's Hospital Affiliated to Shanghai Jiaotong University

andrewssmu@126.com+86 18930173280

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 15, 2026