Effect of preoperative two weeks of high protein intake on postoperative malnutrition in elderly patients undergoing total knee arthroplasty

To evaluate the impact of multi-modal nutritional support on the homeostasis and early postoperative rehabilitation of elderly patients with total joint arthroplasty-A prospective, randomized, double-blind controlled study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000041094

Enrollment

Unknown

Registered

2020-12-17

Start date

2020-12-18

Completion date

Unknown

Last updated

2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total Knee Arthroplasty

Interventions

Group A:Two weeks before surgery, the patient received 2 times the recommended daily protein intake

Group B:No dietary intervention

Eligibility

Sex/Gender

All

Age

60 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients undergoing total knee arthroplasty due to end-stage osteoarthritis and rheumatoid arthritis; patients with an average daily protein intake of less than 0.8g/kg/d for more than half a year before surgery, patients between 60 and 85 years old.

Exclusion criteria

Exclusion criteria: 1. Patients with knee stiffness or rigidity; 2. Previous history of knee surgery; anemia (female 30 or <20 (kg/?); 10. American Society of Anesthesiologists (ASA) 4 or 5 patients.

Design outcomes

Primary

Measure	Time frame
The rate of postoperative hypoproteinemia;	—

Secondary

Measure	Time frame
albumin;Transferrin;Prealbumin;Number and amount of albumin infusion;Hemoglobin;Number and amount of blood transfusion;Incision-related complications;Postoperative hospital stay;Patient satisfaction;	—

Countries

China

Contacts

Public ContactDeli Wang

Peking University Shenzhen Hospital

wangdelinavy@163.com+86 18823463328

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026