Sleep disorder of women at later stages of pregnancy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Participant age: 18 - 45years; (2) The third trimester (28-40 weeks); (3) All participants provided informed consent; (4) Willing to take feces and blood samples; (5) Participants did not suffer from any gastrointestinal disorder and did not experience regular or intermittent gastrointestinal discomfort in the past two years; (6) none of the participants had been treated with antibiotics during the past 1 year; (7) none of the participants had been treated with probiotics in past one month; (8) Regular three meals a day, no diet and vegetarian, no diet and vegetarian.
Exclusion criteria
Exclusion criteria: (1) Severe physical illness, allergy or mental illness; (2) Disturbed by a sleep disorder before pregnancy; (3) Taking sleeping pills or other psychiatric medications before and during pregnancy; (4) Have high blood pressure or diabetes; (5) Take up flying or night shift work before pregnancy; (6) Taking probiotics or antibiotics; (7) Diagnosed severe malnutrition or underweight; (8) Can not cooperate to complete the study; (9) Other conditions are not considered suitable for inclusion by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| 5-HT;?--GABA; | — |
Countries
China
Contacts
Chongqing Health Center for Women and Children