Pancreatic cancer
Conditions
Interventions
Sponsors
The First Affiliated Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 18 to 80 years, regardless of gender; (2) Patients confirmed adenocarcinoma of pancreatic body and tail duct, without distant metastasis.Resectable or borderline resectable pancreatic adenocarcinoma follow 2020 V1 NCCN; (3) Eastern Cooperative Oncology Group (ECOG) performance status 0 to 1; (4) The expected postoperative survival >= 3 months; (5) Follow-up in time and ability to comply with research plans and other program requirements; (6) Volunteer to be the subject and sign the informed consent. (7) Normal hematological index (Leukocyte, platelet, liver function, renal function, DIC, electrolyte index, Hb >10g/dL).
Exclusion criteria
Exclusion criteria: (1) Patients have contraindication to surgery; (2) Patients confirmed locally advanced or unresectable pancreatic cancer (refer to 2020.V1 version of NCCN Pancreatic Cancer Guidelines); (3) Imaging studies found distant metastases; (4) Patients with severe impairment of cardiac, liver or kidney function (Cardiac function grade 3-4, ALT or AST exceeds 5 times the upper limit of normal value, Creatinine exceeds the upper limit of normal); (5) Pregnant or lactating female patients; (6) Patients with other malignant tumors or hematological diseases; (7) Patients have participated in other clinical trials of pancreatic cancer within three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival;RFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative morbidity;Postoperative hospital stays;Total charge;Operative time;Blood loss;Pain score (VSA);R0 resection rate;30-day mortality or in-hospital mortality;POPF (postoperative pancreatic fistula); | — |
Countries
China
Contacts
Public ContactChunlin Ge
The First Affiliated Hospital of China Medical University
Outcome results
None listed