Predictive value of serum microRNA on effect of acupuncture in patients with premature ovarian insufficiency: a nested case-control study

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000041021

Enrollment

Unknown

Registered

2020-12-16

Start date

2020-12-21

Completion date

Unknown

Last updated

2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premature ovarian insufficiency

Interventions

effective group vs non effective group:Nil

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Aged 18-40 years; 2) Meet the diagnostic criteria of POI or in the subclinical stage of POI.

Exclusion criteria

Exclusion criteria: 1) Patients with polycystic ovary syndrome, hyperprolactinemia, hyperandrogenism, hypothyroidism, adrenocortical hypofunction and other endocrine diseases that affect ovulation; 2) Patients with severe cardiovascular and cerebrovascular diseases, nephropathy ,hepatopathy, malignant tumor, hematopoietic diseases and mental disease; 3) Patients who refused to sign informed consent.

Design outcomes

Primary

Measure	Time frame
microRNA;AFC;	—

Secondary

Measure	Time frame
AMH;basal serum level of FSH, LH and E2;Numbers of retrieved oocytes;clinical pregnancy;	—

Countries

China

Contacts

Public ContactHuangfang Xu

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences

15711082019@126.com+86 10-64089736

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026