dry eye
Conditions
Interventions
Group 3m:wear ook 3m
Group 6m:wear ook 6m
Group12m:wear ook 12m
Group 24m:wear 24m
Group 36m:wear ook 36m
Sponsors
Affiliated Second Hospital of Zhejiang University
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: In this prospective study, participants (age range 10–18 years;male or female, spherical refraction 1.00 to 7.00D; corneal astigmatism <= 1.50D) were recruited from The Second Affiliated Hospital of Zhejiang Chinese Medical University.
Exclusion criteria
Exclusion criteria: 1. Active ocular infection. Such as infectious, viral, chlamydial, or immunologic conjunctivitis 2. BUT 0s. 3. Intraocular, corneal refractive surgery, keratoplasty or ocular laser surgery within 6 months. 4. Glaucoma, systemic or ocular diseases that might interfere with tear film production or function. 5. Acute infectious disease of the eyelids, obvious eyelid or ocular surface disorders. 6. Severe MGD. 7. Any serious ocular systemic disease or uncontrolled medical condition. 8. Exposure to any investigational drug within 30 days of study start.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear break up time;Limbal Vogt fence density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal fluorescein staining;Schirmer test;Meibomian gland loss range;Corneal nerve density;Corneal limbus basal cell density;endothelium density;inflammation cell density; | — |
Countries
China
Contacts
Public ContactXiaodan Huang
Affiliated Second Hospital of Zhejiang University
Outcome results
None listed