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Clinical observation for different methods to treat cataract with diabetic macular edema

Clinical observation for different methods to treat cataract with diabetic macular edema

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000041014
Enrollment
Unknown
Registered
2020-12-16
Start date
2020-12-31
Completion date
Unknown
Last updated
2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cataract with diabetic macular edema

Interventions

two step therapy group:Cataract extraction was performed 5-7 days after intravitreal injection of anti VEGF
combined treatment group:Phacoemulsification combined with intravitreal injection of anti VEGF

Sponsors

Tianjin First Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All patients have stable control of blood pressure, blood glucose, blood lipids and other indicators, and no other serious systemic diseases except for type 2 diabetes; all patients undergo medical diagnosis and treatment before surgery, fasting blood glucose is controlled below 8.3mmol/L, and glycosylated hemoglobin is controlled at 5%- 7%; blood pressure is controlled below 150/90mmHg; blood lipid level is controlled within the normal range. 2. All patients underwent visual acuity, intraocular pressure, slit lamp, fundus mirror, fundus fluorescein angiography, and optical coherence tomography examination, with moderate cataract, nuclear 2-3 grade; 3. The patient's eye examination showed non-proliferative diabetic retinopathy with mild to moderate DME (CMT 250µm-450µm); 4. The patients and their families voluntarily participated in the study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Poor control of preoperative blood pressure, blood sugar, blood lipids and other indicators; 2. Patients with severe cardiovascular and cerebrovascular diseases, insufficiency of major organs, who cannot tolerate surgery; 3. Patients who have a history of ocular trauma, glaucoma, high myopia, other eye diseases, or other internal eye surgery that may affect the evaluation of postoperative efficacy before being enrolled; 4. Those who cannot adhere to follow-up and treatment.

Design outcomes

Primary

MeasureTime frame
central macular thickness;

Secondary

MeasureTime frame
best corrected visual acuity;intraocular pressure;Previous section;

Countries

China

Contacts

Public ContactMa Cheng

Tianjin First Central Hospital

macheng2013824@163.com+86 18622654586

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026