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The safety and efficiency of ultrasound-guided percutaneous transhepatic portal pressure gradient measurement for patients with portal hypertension in liver cirrhosis.

The safety and efficiency of ultrasound-guided percutaneous transhepatic portal pressure gradient measurement for patients with portal hypertension in liver cirrhosis.

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000041002
Enrollment
Unknown
Registered
2020-12-16
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Portal hypertesion in cirrhosis

Interventions

Gold Standard:HVPG/PPG measurement in TIPS
Index test:PPG&#32
in&#32
transhepatic&#32

Sponsors

The First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Aged 80 to 18 years; 2.Liver cirrhosis with portal hypertesion; 3.Liver cirrhosis with esophageal and gastric varices; 4.Liver cirrhosis with esophagogastric variceal hemorrhage. 5.Patients who sign the informed consent.

Exclusion criteria

Exclusion criteria: 1.Absolute contraindication:Unable to lie flat; unable to tolerate procedure; 2.Relative contraindications: 1)severe coagualtion dysfunction(INR > 1.6); 2)severe cardiac/pulmonary/kidney failure; 3)incooperate; 4)Extrahepatic biliary tract obstruction; 5)Biliary tract infection; 6)Uncorrectable abodominal ascites; 7)liver amyloidosis; 8)polycystic liver; 9)massive hepatic carcinoma.

Design outcomes

Primary

MeasureTime frame
portal pressure gradient;

Countries

China

Contacts

Public ContactWei Wu

The First Affiliated Hospital of Wenzhou Medical University

wwwwwuwei@126.com+86 13566290340

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026