Breast cancer
Conditions
Interventions
observation group:drug-loaded microsphere embolization+Conventional intravenous chemotherapy
Control group:Conventional intravenous chemotherapy
Sponsors
People's Hospital of Jianyang City, Sichuan Province
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years, males or females; 2. Newly diagnosed patients with unresectable breast cancer or patients who want to down-staging and conserve their breast confirmed by histopathological or clinical diagnosis; 3. ECOG <= 2; 4. The pregnancy test for women of childbearing age must be negative or the patients must agree to use effective contraception during the treatment period and within 1 year thereafter.
Exclusion criteria
Exclusion criteria: 1. The breast cancers that can be surgically removed; 2. The patienta with poor coagulation function, INR > 1.5, or are receiving anticoagulant therapy or suffering known hemorrhagic disease; 3. The patients with unstable coronary heart disease or recent myocardial infarction (within one year); 4. Antibiotics are needed for patients with recent infection; 5. WBC 2mg / L); 7. AST and / or ALT > 3 x ULN; 8. There are comorbidities or social environment that can cause the subjects to fail to follow the research plan or even endanger the safety of patients; 9. The patient was accompanied with other primary tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ORR;PCR;tumor necrosis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of quality of life;adverse reactions; | — |
Countries
China
Contacts
Public ContactJingjun Zhang
People's Hospital of Jianyang City, Sichuan Province
Outcome results
None listed