Metabolic fatty liver disease
Conditions
Interventions
Sponsors
Shuguang Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The diagnostic criteria of mafld were met; 2. According to the TCM syndrome differentiation standard of spleen deficiency and phlegm dampness with blood stasis syndrome; 3. The age ranged from 18 to 65 years old; 4. They voluntarily accepted the treatment of shengefang and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute fatty liver of pregnancy, Reye syndrome (acute encephalopathy complicated with visceral steatosis syndrome), lipoid deposition disease, focal fatty liver, hepatic fatty tumor, etc. 2. Viral hepatitis, drug-induced liver disease, total parenteral nutrition, hepatolenticular degeneration, autoimmune liver disease and other specific diseases can lead to fatty liver. 3. Alt, AST >= 5 x ULN, or TBIL >= 5 x ULN. 4. He took liver protecting drugs, lipid-lowering and weight-loss drugs within 2 weeks before entering the group. 5. Patients with heart, brain, kidney (BUN > 1.5 times of the upper limit of normal value, SCR > upper limit of normal value), hematopoietic system and other serious primary diseases, psychosis and clinically significant abnormal ECG. 6. A woman who is pregnant or ready to conceive, a lactating woman. 7. Those who are known to be allergic to ingredients of shengefang or allergic constitution. 8. Patients suspected of having a history of drug abuse or indeed reducing the possibility of enrollment. 9. Cognitive dysfunction can not give full informed consent. 10. Patients who participated in other clinical trials in the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of proton density and fat content in magnetic resonance imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function;blood fat;FibroScan;BMI;TCM clinical symptom score; | — |
Countries
China
Contacts
Public ContactLyu Jia
Shuguang Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Outcome results
None listed