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The study of association with serum HBcrAg and durability of Interferon-induced Hepatitis B Surface Antigen Seroclearance

The study of association with serum HBcrAg and durability of Interferon-induced Hepatitis B Surface Antigen Seroclearance

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040971
Enrollment
Unknown
Registered
2020-12-16
Start date
2020-12-20
Completion date
Unknown
Last updated
2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic hepatitis B

Interventions

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Sponsors

Beijing Youan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Ages 18 to 60, regardless of gender; (2) All patients with chronic HBV infection were stopped after HBsAg clearance obtained by interferon or combined WITH NA treatment; (3) The baseline clinical types of patients with chronic HBV infection include: HBEag-positive CHB (EP-CHB), Hbeag-negative CHB (EN-CHB), inactive HBsAg carrier (IHC), and DRUG-resistance CHB (DR-CHB). (4) Add informed consent to the cohort follow-up.

Exclusion criteria

Exclusion criteria: (1) CO-infection of HIV, HAV, HCV and HDV, decompensated cirrhosis, liver cancer, autoimmune liver disease, etc.; (2) All relapsed patients were asked about their medical history in detail, and immunosuppressive drugs, cytotoxic drugs, hormones and other drug histories were excluded; (3) Exclude recent blood transfusion, unclean injection and tattoo history; (4) Those who signed the informed consent at the time of registration but could not cooperate during the follow-up were excluded; Those who do not understand the content of the informed consent and cannot sign it; Other things the researchers think.

Design outcomes

Primary

MeasureTime frame
HBcrAg;

Countries

China

Contacts

Public ContactRen Shan

Beijing Youan Hospital, Capital Medical University

13811361553@163.com+86 13811361553

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026