Regulation of Glucose and Lipid Metabolism by Natto and Red Yeast Rice on Patients with Dyslipidemia

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040946

Enrollment

Unknown

Registered

2020-12-16

Start date

2021-03-01

Completion date

Unknown

Last updated

2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dyslipidemia

Interventions

control group:Placebo capsules

Natto:Natto Capsules

Red yeast rice:Red Yeast Capsules

Natto and Red Yeast:Natto and Red Yeast Capsules

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18-65 years. 2.18.5 = 5.2 mmol/L (20 mg/dL) and TG >= 1.7 mmol/L (150 mg/dL). 5.<= 5% change in body weight within past three months.

Exclusion criteria

Exclusion criteria: 1. Pregnant, planning to become pregnant, and women who are breastfeeding. 2. Currently taking or have taken any drugs that affect blood sugar and blood lipids/blood cholesterol (such as insulin, statins, etc.) in the past six months. 3. Suffering from cardiovascular related diseases. 4. Suffering from tumor. 5. Suffering from type 1/2 type diabetes. 6. Suffering from untreated thyroid disease. 7. Suffering from severe liver disease (such as hepatitis, severe fatty liver, etc.). 8. Suffering from kidney disease (such as nephritis, kidney stones, etc.). 9. Having a bleeding tendency or take aspirin. 10. Unable to draw blood due to physical or personal reasons. 11. Surgery has been performed within 3 months before the screening visit 12. Having received large number of glucocorticoid treatments (such as prednisone, methylprednisolone, betamethasone, beclomethasone propionate, depot, prednisolone, hydrocortisone ,Dexamethasone) within 3 months. 13. Having consumed natto/red yeast or health products containing natto/red yeast within 3 months.

Design outcomes

Primary

Measure	Time frame
TC;TG;LDL-C;HDL-C;	—

Secondary

Measure	Time frame
ApoA-1;Fasting blood glucose;Fasting insulin;ALT;AST;Creatinine;Blood urea;	—

Countries

China

Contacts

Public ContactLili Yang

Sun Yat-Sen University

yangll7@mail.sysu.edu.cn+86 13202541566

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026