Colorectal Cancer
Conditions
Interventions
experimental group:Orally take Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus cereus Tablets
Sponsors
The Second Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Informed consent; 2.Preoperative pathological diagnosis of colorectal cancer; 3.Patients who need postoperative radiotherapy and chemotherapy after partial colorectal resection; 4.The patients were in good condition, aged 40-70 years.
Exclusion criteria
Exclusion criteria: 1. The patients had severe heart, lung, kidney, liver dysfunction and metabolic diseases; 2. Distant metastasis detected; 3. Those who are allergic to Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus cereus Tablets; 4. The patient had no serious complications before the operation and had not received radiotherapy or chemotherapy; 5. Those who have immune disease, cannot take orally or absorb digestive tract drugs or are allergic to probiotics; 6. Pregnant and lactating women; 7. During the study period, it may be necessary to use drugs prohibited by clinical trial protocol, such as antibiotics and other drugs affecting intestinal flora; 8. Patients with autoimmune disease, immunodeficiency disease, or history of organ transplantation; 9. Participate in clinical trials of other anti-tumor drugs within 30 days before enrollment; 10. Patients who were considered unsuitable for this study were considered by the researchers.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| High throughput sequencing of feces;Metabolomics of feces;High throughput sequencing of intestinal juice;Metabolomics of intestinal juice;Blood routine;Liver function tests;Renal function tests; | — |
Countries
China
Contacts
Public ContactDeng Xiaorong
The Second Affiliated Hospital of Nanchang University
Outcome results
None listed