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Evaluation of the effect of Clostridium butyricum on adjuvant treatment of patients undergoing gastrectomy

Evaluation of the effect of Clostridium butyricum on adjuvant treatment of patients undergoing gastrectomy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040915
Enrollment
Unknown
Registered
2020-12-15
Start date
2020-12-01
Completion date
Unknown
Last updated
2022-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer

Interventions

experimental group:Orally take Clostridium butyricum Capsule

Sponsors

The Second Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Informed consent; 2. Gastric cancer was confirmed by clinical pathology; 3. The patient is generally in good condition, aged 18-70 years, without serious heart, lung, kidney, liver dysfunction and metabolic diseases; 4. No distant metastatic lesions were found; 5. The patient had no serious complications before the operation, and had not received radiotherapy or chemotherapy.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart, lung, kidney, liver dysfunction and metabolic diseases; 2. Distant metastasis was found; 3. Severe complications were found before surgery and received radiotherapy and chemotherapy; 4. Those who have immune diseases, cannot take orally or absorb digestive tract drugs or are allergic to probiotics; 5. Pregnant and lactating women; 6. Those with a history of allergies to test drugs or similar drugs, allergic physique, or current allergic diseases; 7. During the study period, it may be necessary to use drugs that are prohibited by the clinical trial protocol, such as antibiotics and other drugs that affect the intestinal flora; 8. Patients with autoimmune disease, immunodeficiency disease, or history of organ transplantation; 9. Participate in clinical trials of other antineoplastic drugs within 30 days before enrollment; 10. Patients with severe constipation after surgery; 11. Patients who were considered unsuitable for this study.

Design outcomes

Primary

MeasureTime frame
Blood routine;liver function;Kidney function;Electrolyte;Serum cytokines;

Secondary

MeasureTime frame
Fecal high-throughput sequencing;Fecal Metabolomics;

Countries

China

Contacts

Public ContactDeng Xiaorong

The Second Affiliated Hospital of Nanchang University

dengxr77@163.com+86 13870889003

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026