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Analysis of effective connections between stereovision related brain areas in amblyopia patients based on resting state functional magnetic resonance (fMRI)

Analysis of effective connections between stereovision related brain areas in amblyopia patients based on resting state functional magnetic resonance (fMRI)

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040912
Enrollment
Unknown
Registered
2020-12-15
Start date
2020-12-19
Completion date
Unknown
Last updated
2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amblyopia

Interventions

amblyopia:non
normal control:non

Sponsors

West China Hospital Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Aged 8 -40 years; 2. Amblyopia group: the best corrected visual acuity of amblyopia eye was = 1.00 D difference between eyes in spherical equivalent;(2) >= 1.50 D difference in astigmatism between corresponding meridians in the 2 eyes strabismus amblyopia:Horizontal or vertical deviation > 15 prisms;or with strabismus history; 3. Normal control group:normal visual acuity (with or without refraction correction) in both eyes; normal binocular visual function; and no history of strabismus or amblyopia or history of treatment; 4. Right-handedness.

Exclusion criteria

Exclusion criteria: 1. Other organic ocular lesions and history; 2. Psychiatric diseases and history; 3. Those who are claustrophobic or unable to cooperate with MRI examination due to metal implants and any other reasons.

Design outcomes

Primary

MeasureTime frame
effective connection;

Secondary

MeasureTime frame
Stereoscopic vision;Fine motor ability;BCVA;

Countries

China

Contacts

Public ContactLiu Longqian

West China Hospital Sichuan University

bq15651@hotmail.com+86 13708000190

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026