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Clinical research of Xinglou Chengqi Decoction on improving post-stroke cognitive impairment due to phlegm heat and viscera excess syndrome based on brain-gut interaction

Clinical research of Xinglou Chengqi Decoction on improving post-stroke cognitive impairment due to phlegm heat and viscera excess syndrome based on brain-gut interaction

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040910
Enrollment
Unknown
Registered
2020-12-15
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke Cognitive Impairment

Interventions

Sponsors

Wenzhou Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The patients met the diagnostic criteria of ischemic stroke in Western medicine. 2. The patients met the diagnostic criteria of vascular cognitive impairment and MMSE score was less than 25. 3. Conformity with the diagnosis of TCM stroke disease name. 4. Within 2 weeks to 6 months from the date of the onset of the disease, the patient has clear consciousness, sufficient visual and auditory abilities, and can cooperate with neuropsychological assessment. 5. Aged 18-85 years (gender without special requirements). 6. Voluntary subjects who sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Lacunar infarction,transient ischemic attack. 2. Stroke patients confirmed by examination to be caused by brain tumors, brain trauma, hematological diseases, etc. 3. Patients with cerebral embolism caused by rheumatic heart disease,coronary heart disease and other cardiac diseases combined with atrial fibrillation. 4. Patients with serious primary diseases such as cardiovascular,liver,kidney,hematopoietic and immune systems,or patients with tumors,psychiatric patients,and those without self-knowledge ability. 5. Pregnant and lactating women,allergic constitution.

Design outcomes

Primary

MeasureTime frame
serum brain-gut peptide;

Secondary

MeasureTime frame
constipation assessment;Mini Mental State Examination Scale (MMSE);

Countries

China

Contacts

Public ContactShixuan Chen

Wenzhou Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine

351644656@qq.com+86 15825665998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026