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A clinical study on the change of pupil diameter in predicting postoperative pain

A clinical study on the change of pupil diameter in predicting postoperative pain

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040908
Enrollment
Unknown
Registered
2020-12-15
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

Gold Standard:Patient complaint
Index test:Pupil&#32
blood&#32

Sponsors

Fourth Medical Center of PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. To be operated on under General Anesthesia; 2. Conscious, without severe systemic disease, ASA I-III; 3. Without eye disease, color vision examination and pupillary reflex examination without abnormality; 4. Both eyes had uncorrected or corrected visual acuity >= 1.0, the absolute value of Myopia/hyperopia or Presbyopia <= 1.00, and no history of eye medication within 5.1 months.

Exclusion criteria

Exclusion criteria: 1. Iris disease, cataract and other eye diseases or traumatic history of patients; 2. Perioperative use of cardiovascular active agents, anticholinesterase/anticholinergic agents; 3. Within 1 month, the use of the drug has an effect on the pupil diameter; 4. Patients with unequal pupil before and after extubation.

Design outcomes

Primary

MeasureTime frame
Pupil diameter;SEN, SPE, ACC, AUC of ROC, PV+, PV-;

Countries

China

Contacts

Public ContactLi Mengmeng

The Fourth Medical Center of PLA General Hospital

mmli304@163.com+86 13401000778

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026